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    Dalmatian bladder stones caused by gene that regulates uric acid in humans

    Posted on November 8, 2008, under Misc

    The discovery equips dog breeders with the tools to eliminate that trait from the Dalmatian breed and yields clues to the cause of similar problems in humans. The findings will be published Nov. 7 in the scientific journal Public Library of Science.

    “This defect, which in dogs is peculiar to the entire Dalmatian breed, has been reported for nearly a century and was probably unintentionally introduced as breeders worked to select more distinctive spotting patterns,” said veterinary geneticist Danika Bannasch, lead author on the study.

    “It is now possible that this trait can be removed from the breed by crossing Dalmatians with the normal offspring of the original Dalmatian-pointer breeding that occurred in the early 1970s,” she said.

    By Dec. 1, the Veterinary Genetics Laboratory in UC Davis’ School of Veterinary Medicine will begin offering DNA testing for the mutation in dogs to allow breeders to eliminate the trait. Information on the testing program will be available online at UC Davis Veterinary Genetics Laboratory

    The researchers collected DNA samples as well as urine samples from hundreds of dogs to identify the gene responsible for high levels of uric acid. Genetic analysis of dogs that are a cross between pointers and Dalmatians revealed that gene to be SLC2A9, a gene that recently has been reported to be important in regulating uric acid levels in humans. DNA analysis showed that mutations in the SLC2A9 gene were responsible for the elevated uric acid in the Dalmatians.

    The same mutations also were present in some bulldogs and black Russian terriers, breeds that are not known to be closely related to Dalmatians. This suggests that the gene mutation must be quite old, even predating formation of the Dalmatian breed. Alternatively, the mutation could have been introduced to those breeds by crosses between breeds, the researchers noted.

    Because the gene mutation does not always occur in bulldogs and black Russian terriers, breeders can simply use genetic selection to eliminate the unhealthy trait from those breeds. In Dalmatians, however, the mutation occurs in all dogs, forcing breeders to look outside of the breed to correct the problem. Download the journal in PDF format

    source:www.physorg.com


    A Very Dairy Christmas – Christmas Gift for Veterinarian

    Posted on December 20, 2008, under Misc

    A Very Dairy Christmas - Christmas Gift for VeterinarianBe prepared to laugh and cry when social tolerance and generational differences are put to the test in this inspirational novel about a New York City pop-culture princess who is unexpectedly forced to visit her estranged German grandparents on their Wisconsin dairy farm during her Christmas vacation. A Very Dairy Christmas emphasizes the true meaning of Christmas in a present-day setting while delivering a message that is sure to inspire the reader!

    With chapters like "There’s no place like a stranger’s home", "You don’t need a farm to have a pig", and Redemption is a mouse click away", you’ll be whisked away into the privileged, and often controversial, world of Callie Michaels, the teenaged daughter of famed high fashion photographer, Zoey Michaels.

    Books become classics when they appeal to all generations, and A Very Dairy Christmas manages to do just that in this heart-warming comedy about dysfunctional family relationships. VIEW DETAILS


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    Atlas of Normal Radiographic Anatomy and Anatomic Variants in the Dog and Cat Reviews

    Posted on February 25, 2011, under Veterinary Book

    Atlas of Normal Radiographic Anatomy and Anatomic Variants in the Dog and Cat
    Featuring hundreds of high-quality digital images, Atlas of Normal Radiographic Anatomy and Anatomic Variants in the Dog and Cat helps you make accurate diagnoses by identifying the differences between normal and abnormal anatomy. Expert authors Donald E. Thrall and Ian D. Robertson describe a wider range of “normal,” as compared to competing books, not only showing standard dogs and cats but non-standard subjects such as overweight and underweight pets plus animals with breed-specific variation

    Bach Flower Remedies for Animals
    This book offers descriptions of each of the 38 Bach Flower remedies and their application to the treatment of range of domestic animals including horses, farm and zoo animals.


    A Very Dairy Christmas – Christmas Gift for Veterinarian

    Posted on December 20, 2008, under Misc

    A Very Dairy Christmas - Christmas Gift for VeterinarianBe prepared to laugh and cry when social tolerance and generational differences are put to the test in this inspirational novel about a New York City pop-culture princess who is unexpectedly forced to visit her estranged German grandparents on their Wisconsin dairy farm during her Christmas vacation. A Very Dairy Christmas emphasizes the true meaning of Christmas in a present-day setting while delivering a message that is sure to inspire the reader!

    With chapters like "There’s no place like a stranger’s home", "You don’t need a farm to have a pig", and Redemption is a mouse click away", you’ll be whisked away into the privileged, and often controversial, world of Callie Michaels, the teenaged daughter of famed high fashion photographer, Zoey Michaels.

    Books become classics when they appeal to all generations, and A Very Dairy Christmas manages to do just that in this heart-warming comedy about dysfunctional family relationships. VIEW DETAILS